The Histone H4 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to H4 clustered histone 15, H4 clustered histone 8, H4 histone 16, H4-16, H4C15, and H4C8. This antibody recognizes Human, Mouse, and Rat antigen. The Histone H4 Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling